Browsing Technological University of the Shannon: Midlands Midwest by Author "Kennedy, James E."
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The development of a melt-extruded shellac carrier for the targeted delivery of probiotics to the colon.
Gately, Noel M.; Kennedy, James E. (MDPI, 2017-12)Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery resulting in improved ... -
Evaluation and characterisation of urinary catheter coating utilising Hansen solubility parameters and FEA analysis.
Carberry, Brendan J.; Farrell, Joseph; Kennedy, James E. (Elsevier, 2015-08-15)This work investigated the Hansen solubility parameters required to optimise a functional polyurethane base coat as an attachment for a lubricious polyvinyl pyrrolidone coating for polyvinyl chloride urinary catheters. ... -
Processing stability and the significance of variation in extrusion speeds and temperture on SSB® 55 Pharma Grade Shellac for Oral Drug Delivery
Gately, Noel M.; Kennedy, James E. (MDPI, 2017-09-06)The melt-extrusion process is utilized in the pharmaceutical arena for the manufacturing of a variety of dosage forms and formulations, including solid dispersions. This technology is considered an efficient and continuous ...