Browsing Technological University of the Shannon: Midlands Midwest by Author "Gately, Noel M."
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Designing sustainable polymer blends: tailoring mechanical properties and degradation behaviour in PHB/PLA/PCL blends in a seawater environment
Engler, Leonardo; Farias, Naiara C.; Crespo, Janaina S.; Gately, Noel M.; Major, Ian; Pezzoli, Romina; Devine, Declan M. (MDPI, 2023-06-29)Biodegradable polyesters are a popular choice for both packaging and medical device manufacture owing to their ability to break down into harmless components once they have completed their function. However, commonly used ... -
The development of a melt-extruded shellac carrier for the targeted delivery of probiotics to the colon.
Gately, Noel M.; Kennedy, James E. (MDPI, 2017-12)Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery resulting in improved ... -
Influence of annealing and biaxial expansion on the properties of Poly-l-lactic) medical tubing.
Dillon, Brian; Doran, Patrick; Fuenmayor, Evert; Healy, Andrew V.; Gately, Noel M.; Major, Ian; Lyons, John G. (MDPI, 2019-07-11)Poly-l-lactic acid (PLLA) is one of the most common bioabsorbable materials in the medical device field. However, its use in load-bearing applications is limited due to its inferior mechanical properties when compared ... -
The influence of low shear microbore extrusion on the properties of high molecular weight poly(l-lactic acid) for medical tubing applications.
Dillon, Brian; Doran, Patrick; Fuenmayor, Evert; Healy, Andrew V.; Gately, Noel M.; Major, Ian; Lyons, John G. (MDPI, 2019-04)Biodegradable polymers play a crucial role in the medical device field, with a broad range of applications such as suturing, drug delivery, tissue engineering, sca olding, orthopaedics, and fixation devices. Poly-l-lactic ... -
Physical properties of shellac material used for hot melt extrusion with potential application in the pharmaceutical industry
Yan, Guangming; Cao, Zhi; Devine, Declan; Penning, Manfred; Gately, Noel M. (MDPI, 2021-10-28)Hot melt extrusion offers an efficient way of increasing the solubility of a poorly soluble drug. Shellac has potential as a pharmaceutical matrix polymer that can be used in this extrusion process, with further advantages ... -
Processing stability and the significance of variation in extrusion speeds and temperture on SSB® 55 Pharma Grade Shellac for Oral Drug Delivery
Gately, Noel M.; Kennedy, James E. (MDPI, 2017-09-06)The melt-extrusion process is utilized in the pharmaceutical arena for the manufacturing of a variety of dosage forms and formulations, including solid dispersions. This technology is considered an efficient and continuous ...