Browsing Technological University of the Shannon: Midlands Midwest by Author "Gately, Noel"
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3D printed polymers are less stable than injection moulded counterparts when exposed to terminal sterilization processes using novel vaporized hydrogen peroxide and electron beam processes.
Chen, Yuanyuan; Neff, Martin; McEvoy, Brian; Cao, Zhi; Pezzoli, Romina; Murphy, Alan; Gately, Noel; Hopkins Jnr, Michael; Rowan, Neil J.; Devine, Declan M. (Elsevier, 2019-11-21)There is an increasing trend for use of 3D printing processes in healthcare due in part to emergence of customised medical devices and associated low manufacturing cost. However, there is a dearth of knowledge on the ... -
Application of biomaterials for complex anal fistulae
Fitzpatrick, Daniel P.; Kealey, Carmel; Brady, Damien; Gately, Noel (Taylor & Francis, 2021-11-07)Complex anal fistulae remain a challenge for the medical sector as conventional treatments put patients at risk of incontinence. Clinicians and researchers have become interested in the application of bioresorbable ... -
Chitosan-(poly)acrylic acid polyelectrolyte complexes: enhanced mucoadhesion and sustained drug release in vaginal tablets
Abidin, Ismin Zainol; Fehrenbach, Gustavo Waltzer; Gately, Noel (Elsevier, 2024-03-08)Polyelectrolyte complexes (PECs) have emerged as promising vehicles for medical applications, attributable to their non-toxicity, non-immunogenicity, and ability for controlled drug release. Notably, their inherent ... -
Development of dental implants with antimicrobial activity
Mulry, Aoife; Kealey, Carmel; Brady, Damien; Gately, Noel (Technological University of the Shannon Midlands Midwest, 2022)Planktonic bacteria are capable of forming biofilms, which are described as microbial aggregates embedded within a matrix of extracellular polymeric substances (EPS) and are found attached to abiotic or biotic surfaces ... -
Hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded delivery system
Yan, Guangming; Cao, Zhi; Devine, Declan; Gately, Noel (TUS Midlands Midwest, 2022)Cardiovascular diseases (CVDs) are the number 1 cause of death globally. Fenofibrate has been shown an excellent treating effect on CVDs. However, Fenofibrate is a neutral, lipophilic compound that is practically insoluble ... -
Mass-customization of oral tablets via the combination of 3D printing and injection molding.
Fuenmayor, Evert; O'Donnell, Crevan; Gately, Noel; Doran, Patrick; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (Elsevier, 2019-10-05)The new frontier of medicine is the personalization of treatment to match a patient’s individual needs. Fused-filament fabrication (FFF) offers a platform for the personalization of drug dosage forms, but one of its chief ... -
A systematic review of mucoadhesive vaginal tablet testing
Abidin, Ismin Zainol; Murphy, Emma J.; Fehrenvbach, Gustavo Waltzer; Rezoagli, Emanuele; Gately, Noel; Major, Ian (AboutScience, 2023-01-16)Drug administration through the vaginal tract is one of the oldest modalities of pharmacotherapy, and it is also one of the most explored. Since the vaginal cavity has a wide surface area, a plentiful blood supply, and a ... -
Treatment for the amelioration of persistent factors in complex anal fistula
Fitzpatrick, Daniel P.; Kealey, Carmel; Brady, Damien; Goodman, Martin; Gately, Noel (Springer, 2021-11-19)Anal fistulae are abnormal hollow connections between the wall of the anal canal and the perianal skin around the anus that have remained a burden on the medical sector for centuries. The complexity of this disease is ...