Browsing Technological University of the Shannon: Midlands Midwest by Author "Fuenmayor, Evert"
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Additive manufacturing of personalized pharmaceutical dosage forms via stereolithography.
Healy, Andrew V.; Fuenmayor, Evert; Doran, Patrick; Geever, Luke M.; Higginbotham, Clement L.; Lyons, John G. (MDPI, 2019-12-03)The introduction of three-dimensional printing (3DP) has created exciting possibilities for the fabrication of dosage forms, paving the way for personalized medicine. In this study, oral dosage forms of two drug ... -
Additive manufacturing of PLA/HNT nanocomposites for biomedical applications
Venkatesh, Chaitra; Fuenmayor, Evert; Doran, Patrick; Major, Ian (Elsevier, 2019)Additive manufacturing has been of great interest of research in various applications due to their ease in processability, cost effectiveness and adaptability. In this study Poly Lactic Acid (PLA) was used as the base ... -
Applications of Digital Twin across industries: a review
Singh, Maulshree; Srivastava, Rupal; Fuenmayor, Evert; Kuts, Vladimir; Qiao, Yuansong; Murray, Niall; Devine, Declan (MDPI, 2022-06-14)One of the most promising technologies that is driving digitalization in several industries is Digital Twin (DT). DT refers to the digital replica or model of any physical object (physical twin). What differentiates DT ... -
Comparison of fused-filament fabrication to direct compression and injection molding in the manufacture of oral tablets.
Fuenmayor, Evert; Forde, Martin; Healy, Andrew V.; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (Elsevier, 2019-03-10)Oral tablets are a convenient form to deliver active pharmaceutical ingredients (API) and have a high level of acceptance from clinicians and patients. There is a wide range of excipients available for the fabrication of ... -
Digital twin: origin to future
Singh, Maulshree; Fuenmayor, Evert; Hinchy, Eoin P.; Qiao, Yuansong; Murray, Niall (MDPI, 2021-05-24)Digital Twin (DT) refers to the virtual copy or model of any physical entity (physical twin) both of which are interconnected via exchange of data in real time. Conceptually, a DT mimics the state of its physical twin ... -
Heat dissipation plays critical role for longevity of polymer-based 3D-printed inserts for plastics injection moulding.
Moritz, Vicente; Bezerra, Gilberto S.N.; Hopkins, Michael Jnr.; Fuenmayor, Evert; Günbay, Suzan; Hayes, Conor; Lyons, John G.; Devine, Declan M. (MDPI, 2022-10-08)Injection moulding is a polymer processing method of choice for making plastic parts on industrial scale, but its traditional mould is made from tooling steel with time-consuming and costly production. Additive manufacturing ... -
Influence of annealing and biaxial expansion on the properties of Poly-l-lactic) medical tubing.
Dillon, Brian; Doran, Patrick; Fuenmayor, Evert; Healy, Andrew V.; Gately, Noel M.; Major, Ian; Lyons, John G. (MDPI, 2019-07-11)Poly-l-lactic acid (PLLA) is one of the most common bioabsorbable materials in the medical device field. However, its use in load-bearing applications is limited due to its inferior mechanical properties when compared ... -
The influence of low shear microbore extrusion on the properties of high molecular weight poly(l-lactic acid) for medical tubing applications.
Dillon, Brian; Doran, Patrick; Fuenmayor, Evert; Healy, Andrew V.; Gately, Noel M.; Major, Ian; Lyons, John G. (MDPI, 2019-04)Biodegradable polymers play a crucial role in the medical device field, with a broad range of applications such as suturing, drug delivery, tissue engineering, sca olding, orthopaedics, and fixation devices. Poly-l-lactic ... -
Integrating 3D printing and injection molding for mass customization: advancements in hybrid manufacturing
Gong, Ke (Technological University of the Shannon: Midlands Midwest, 2023-08)Additive manufacturing (AM) is renowned for its ability to create complex geometries and customized products but is limited by low throughput. Conversely, injection molding (IM) excels in high-volume production but ... -
Liquid-based 4D printing of shape memory nanocomposites: a review
Alsaadi, Mohamad; Hinchy, Eoin P.; McCarthy, Conor T.; Moritz, Vicente F.; Zhuo, Shuo; Fuenmayor, Evert; Devine, Declan M. (MDPI, 2023-01-31)Significant advances have been made in recent years in the materials development of liquidbased 4D printing. Nevertheless, employing additive materials such as nanoparticles for enhancing printability and shape memory ... -
Mass customization of polylactic acid (PLA) parts via a hybrid manufacturing process
Gong, Ke; Liu, Handai; Huang, Cheng; Jiang, Qinyu; Xu, Han; Cao, Zhi; Fuenmayor, Evert; Major, Ian (MDPI, 2022-12-10)Mass customization is the development of items tailored to specific customers, but produced at low unit cost in high-volume. In this context, hybrid manufacturing (HM) combines fused deposition modeling (FDM) and injection ... -
Mass-customization of oral tablets via the combination of 3D printing and injection molding.
Fuenmayor, Evert; O'Donnell, Crevan; Gately, Noel; Doran, Patrick; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (Elsevier, 2019-10-05)The new frontier of medicine is the personalization of treatment to match a patient’s individual needs. Fused-filament fabrication (FFF) offers a platform for the personalization of drug dosage forms, but one of its chief ... -
Material considerations for fused-filament fabrication of solid dosage forms.
Fuenmayor, Evert; Forde, Martin; Healy, Andrew V.; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (MDPI, 2018-04)Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ... -
Material considerations for fused-filament fabrication of solid dosage forms.
Fuenmayor, Evert; Forde, Martin; Healy, Andrew M.; Devine, Declan M.; Lyons, John G.; McConville, Christopher; Major, Ian (MDPI, 2018-04-02)Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ... -
A novel manufacturing technique for the production of tailored solid dosage forms
Fuenmayor, Evert (Athlone Institute of Technology, 2020)The main objective of this study was to evaluate manufacturing processes for the fabrication of tailored solid dosage forms. Two hot-melt extrusion based manufacturing processes were investigated, a 3D printing process ... -
Polymer based additive manufacturing historical developments, process types and material considerations.
Pollack, Steven; Venkatesh, Chaitra; Neff, Martin; Hu, Guang; Fuenmayor, Evert; Lyons, John G.; Major, Ian; Devine, Declan M. (Springer Nature, 2019)3D printing is a manufacturing technique where parts are built in a layer-by-layer fashion. The earliest embodiments were based on generating successive layers of solidified materials at the air liquid interface through ... -
Production and testing of the flat faced tablets via overprinting of injection moulded tablet bases
Xu, Han; Major, Ian; Fuenmayor, Evert (Technological University of the Shannon Midlands Midwest, 2022)Conventional drug production assures the merits of maintaining unit dosage form accuracy, stable dose and invariability among the batches. It also has a shortcoming that cannot make personalised medicine that could target ... -
Production and testing of the flat faced tablets via overpriting of injection moulded tablet bases
Xu, Han (Athlone Institute of Technology, 2020-06)The pharmaceutical industry is exploring the realization of tailored dosage forms for individual patients to provide precision medicine. My supervisors have previously used a hybrid manufacturing technique that overmoulded ... -
The production of solid dosage forms from non-degradable polymers.
Major, Ian; Fuenmayor, Evert; McConville, Christopher (Bentham Science, 2015)Non-degradable polymers have an important function in medicine. Solid dosage forms for longer term implantation require to be constructed from materials that will not degrade or erode over time and also offer the utmost ... -
Tailoring drug release in bilayer tablets through droplet deposition modeling and injection molding
Ebrahimi, Farnoosh; Xu, Han; Fuenmayor, Evert; Major, Ian (Elsevier, 2024-02-01)This study explores the innovative production of personalized bilayer tablets, integrating two advanced manufacturing techniques: Droplet Deposition Modeling (DDM) and Injection Molding (IM). Unlike traditional methods ...