Browsing Technological University of the Shannon: Midlands Midwest by Author "Cao, Zhi"
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3D printed polymers are less stable than injection moulded counterparts when exposed to terminal sterilization processes using novel vaporized hydrogen peroxide and electron beam processes.
Chen, Yuanyuan; Neff, Martin; McEvoy, Brian; Cao, Zhi; Pezzoli, Romina; Murphy, Alan; Gately, Noel; Hopkins Jnr, Michael; Rowan, Neil J.; Devine, Declan M. (Elsevier, 2019-11-21)There is an increasing trend for use of 3D printing processes in healthcare due in part to emergence of customised medical devices and associated low manufacturing cost. However, there is a dearth of knowledge on the ... -
Alfa fiber/polypropylene composites: Influence of fiber extraction method and chemical treatments.
Labidi, Khaled; Cao, Zhi; Murphy, Alan; Hamzaoui, Ahmed Hichem; Devine, Declan M. (Wiley, 2019-01)Alfa fiber/polypropylene composites were manufactured using twin-screw extrusion. Fibers were extracted following alkaline and steam explosion methods. Three chemical treatments were also applied to alkaline extracted ... -
A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
Abidin, Ismin Zainol; Rezoagli, Emanuele; Simonassi-Paiva, Bianca; Fehrenbach, Gustavo Waltzer; Masterson, Kevin; Pogue, Robert; Cao, Zhi; Rowan, Neil; Murphy, Emma J.; Major, Ian (MDPI, 2020-12-06)This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to reduce relapse by eradicating ... -
Bone tissue engineering scaffold optimisation through modification of Chitosan/ceramic composition
Zhou, Keran; Azaman, Farah Alwani; Cao, Zhi; Brennan Fournet, Margaret; Devine, Declan M. (MDPI, 2023-06-01)A large bone defect is defined as a defect that exceeds the regenerative capacity of the bone. Nowadays, autologous bone grafting is still the gold standard treatment. In this study, a hybrid bone tissue engineering scaffold ... -
Characteristics of the treated calcium carbonate particles with stearic acid using different treating methods.
Cao, Zhi; Daly, Michael; Clémence, Lopez; Major, Ian; Higginbotham, Clement L.; Devine, Declan M. (Elsevier, 2016-08)Calcium carbonate (CaCO3) is often treated with stearic acid (SA) to decrease its polarity. However, the method of application of the SA treatments has a strong influence on their interface structure and distribution. ... -
Development of a new bone scaffold for the treatment of large bone defects
Zhou, Keran; Brennan-Fournet, Margaret; Cao, Zhi; Devine, Declan (Technological University of the Shannon Midlands Midwest, 2022)Large bone defects remains a major problem in orthopaedic surgery despite these advances in medical techniques. To date, autogenous bone grafting is still commonly therapeutic standard. However, it presents some ... -
Development of high strength nanocomposite for biodegradable stents
Venkatesh, Chaitra; Chen, Yuanyuan; Cao, Zhi; Brennan, Shane; Major, Ian; Lyons, John G.; Devine, Declan M. (Athlone Institute of Technology, 2018-04-24)The use of biodegradable polymer materials are considered to be good alternatives in urology (Donohue et. al. 2018), cardiovascular (Brie et. al. 2016) and tracheal airway stenosis which provide support before it is absorbed ... -
Development, characterization and cell viability inhibition of PVA spheres loaded with Doxorubicin and 4′-Amino-1-Naphthyl-Chalcone (D14) for osteosarcoma
Seba, Viviane; de Lima, Gabriel Goetten; Periera, Bruno Leandro; Silva, Gabriel; Reinhardt, Luiza Steffens; Arantes, Pablo Ricardo; Shee, Bor Shin; dos Santos, Maria Bastos; França, Suzelei C.; Regasini, Luis Octavio; Fachin, Ana Lúcia; Cao, Zhi; Nugent, Michael J.D.; Marins, Mozart (MDPI, 2021-08-06)Chalcones (1,3-diaryl-2-propen-1-ones) are naturally occurring polyphenols with known anticancer activity against a variety of tumor cell lines, including osteosarcoma (OS). In this paper, we present the preparation and ... -
Effect of Chemical Treatments and HDPE-g-MA on the physical and mechanical behaviour of HDPE/ natural fibre composites.
Cao, Zhi; Peyregne, Marc; Daly, Michael; Mullen, Tom; Devine, Declan M.; Geever, Luke; Higginbotham, Clement L. (2013)Many authors have reported on the use of natural fibres (raw or chemically modified) as reinforcing elements for high density polyethylene (HDPE). These materials have generated a lot of interest due to their low cost ... -
Effect of thermal annealing on a bilayer polyvinyl alcohol/polyacrylic acid electrospun hydrogel nanofibres loaded with doxorubicin and clarithromycin for a synergism effect against osteosarcoma cells
Chee, Bor Shin; de Lima, Gabriel Goetten; de Lima, T.A.M.; Seba, Viviane; Lemarquis, C.; Pereira, Bruno Leandro; Bandeira, Marina; Cao, Zhi; Nugent, Michael J.D. (Elsevier, 2021-08-02)Polyvinyl alcohol/polyacrylic acid (PVA/PAA) bilayer hydrogel nanofibres were successfully fabricated by electrospinning and physically crosslinked via heat treatment. The effects of the thermal annealing process on the ... -
Enhancing drug solubility through advanced polymer extruded shellac-based matrix drug delivery systems
Yan, Guangming (Technological University of the Shannon: Midlands Midwest, 2022-09)The main objective of this study is to enhance the solubility of the model drug fenofibrate, by forming amorphous solid dispersions using a hot melt extrusion process. Hot melt extrusion offers an efficient way of ... -
An ensemble machine learning method for microplastics identification with FTIR spectrum
Yan, Xinyu; Cao, Zhi; Murphy, Alan; Qiao, Yuansong (Elsevier, 2022-06-20)Microplastics (MPs) (size < 5 mm) marine pollution have been investigated and monitored by many researchers and found in many coasts around the world. These toxic chemicals make their way into human diet through food ... -
Granule-based material extrusion is comparable to filament-based material extrusion in terms of mechanical performances of printed PLA parts: a comprehensive investigation
Liu, Handai; Gong, Ke; Portela, Alexandre; Cao, Zhi; Dunbar, Ronan; Chen, Yuanyuan (Elsevier, 2023-08-05)To implement a circular economic life for thermoplastic waste, such as polylactic acid (PLA) waste from filament-based material extrusion (FME) printing and reduce the costs associated with producing filaments for the FME ... -
Hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded delivery system
Yan, Guangming; Cao, Zhi; Devine, Declan; Gately, Noel (TUS Midlands Midwest, 2022)Cardiovascular diseases (CVDs) are the number 1 cause of death globally. Fenofibrate has been shown an excellent treating effect on CVDs. However, Fenofibrate is a neutral, lipophilic compound that is practically insoluble ... -
Hybrid manufacturing 3D printing and injection moulding in the pursuit of mass customization
Gong, Ke; Major, Ian; Devine, Declan; Cao, Zhi (Athlone Institute of Technology, 2020-06)Project Overview: Mass customization is a marketing and manufacturing technique which combines the flexibility and personalization of custom-made products with the low unit costs associated with mass production. The ... -
Influence of extrusion screw speed on the properties of halloysite nanotube impregnated polylactic acid nanocomposites
Venkatesh, Chaitra; Chen, Yuanyuan; Cao, Zhi; Brennan, Shnae; Major, Ian; Lyons, John G.; Devine, Declan M. (De Gruyter, 2021)Poly (lactic acid)/halloysite nanotube (PLA/HNT) nanocomposites have been studiedextensively over the past fewyears owing to the interesting properties of the polymer, PLA, and the nanoclay, HNT, individually and as ... -
Integrating 3D printing and injection molding for mass customization: advancements in hybrid manufacturing
Gong, Ke (Technological University of the Shannon: Midlands Midwest, 2023-08)Additive manufacturing (AM) is renowned for its ability to create complex geometries and customized products but is limited by low throughput. Conversely, injection molding (IM) excels in high-volume production but ... -
Mass customization of polylactic acid (PLA) parts via a hybrid manufacturing process
Gong, Ke; Liu, Handai; Huang, Cheng; Jiang, Qinyu; Xu, Han; Cao, Zhi; Fuenmayor, Evert; Major, Ian (MDPI, 2022-12-10)Mass customization is the development of items tailored to specific customers, but produced at low unit cost in high-volume. In this context, hybrid manufacturing (HM) combines fused deposition modeling (FDM) and injection ... -
"My heart, your heart"; hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded drug delivery system
Yan, Guangming; Cao, Zhi; Devine, Declan; Gatley, Noel (Athlone Institute of Technology, 2020-06)Cardiovascular diseases (CVDs) are the number 1 cause of death globally. Fenofibrate has been shown an excellent treating effect on CVDs. However, Fenofibrate is a neutral, lipophilic compound that is practically insoluble ... -
Nanofillers can be used to enhance the thermal conductivity of commercially available SLA resins.
Hu, Guang; Cao, Zhi; Hopkins, Michael; Lyons, John G.; Brennan-Fournet, Margaret; Devine, Declan M. (Elsevier, 2019-06)Stereolithography (SLA) is a form of 3D printing technology used for the production parts and patterns in a layer by layer fashion. Traditionally, 3D printing has been used for the manufacture of prototypes, however it is ...