Browsing Technological University of the Shannon: Midlands Midwest by Author "Berry, Donagh P."
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Associations between the K232A polymorphism in the diacylglycerol-O-transferase 1 (DGAT1) gene and performance in Irish Holstein-Friesian dairy cattle
Berry, Donagh P.; Howard, Dawn; O'Boyle, P.; Waters, S.; Kearney, J. F.; McCabe, M. (Teagasc, 2010)Selection based on genetic polymorphisms requires accurate quantification of the effect or association of the polymorphisms with all traits of economic importance. The objective of this study was to estimate, using progeny ... -
DNA sequence polymorphisms in a panel of eight candidate bovine imprinted genes and their association with performance traits in Irish Holstein-Friesian cattle.
Magee, David A.; Sikora, Klaudia M.; Berowicz, Erik W.; Berry, Donagh P.; Howard, Dawn J.; Mullen, Michael P.; Evans, Ross D.; Spillane, Charles; MacHugh, David E. (BMC, 2010-10-13)Background: Studies in mice and humans have shown that imprinted genes, whereby expression from one of the two parentally inherited alleles is attenuated or completely silenced, have a major effect on mammalian ... -
DNA sequence polymorphisms within the bovine guanine nucleotide-binding protein Gs subunit alpha (Gsα)-encoding (GNAS) genomic imprinting domain are associated with performance traits
Kikora, Klaudia M.; Magee, David A.; Berkowicz, Erik W.; Berry, Donagh P.; Howard, Dawn; Mullen, Michael P.; Evans, Ross D.; MacHugh, David E.; Spillane, Charles (BMC, 2011-01-11)Background: Genes which are epigenetically regulated via genomic imprinting can be potential targets for artificial selection during animal breeding. Indeed, imprinted loci have been shown to underlie some important ... -
Integrative genomics of the mammalian alveolar macrophage response to intraceullular mycobacteria
Hall, Thomas J.; Mullen, Michael P.; McHugo, Gillian; Killick, Kate E.; Ring, Siobhán C.; Berry, Donagh P.; Correia, Carolina N.; Browne, John A.; Gordon, Stephen V.; MacHugh, David E. (BMC, 2021)Bovine TB (bTB), caused by infection with Mycobacterium bovis, is a major endemic disease affecting global cattle production. The key innate immune cell that first encounters the pathogen is the alveolar macrophage, ... -
Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples
Mullen, Michael P.; Creevey, Christopher J.; Berry, Donagh P.; McCabe, Matt S.; Magee, David A.; Howard, Dawn J.; Killeen, Aideen P.; Park, Stephen D.; McGettigan, Paul A.; Lucy, Matt C.; MacHugh, David E.; Waters, Sinead M. (BMC, 2012-01-11)Background: The central role of the somatotrophic axis in animal post-natal growth, development and fertility is well established. Therefore, the identification of genetic variants affecting quantitative traits within ... -
Single nucleotide polymorphisms in the insulin-like growth factor 1 (IGF-1) gene are associated with performance in Holstein-Friesian dairy cattle.
Mullen, Michael P.; Berry, Donagh P.; Howard, Dawn; Diskin, Michael G.; Lynch, Ciaran O.; Gibliin, Linda; Kenny, David A.; Meade, Kieran G.; Waers, Sinead (Frontiers, 2011-02-16)Insulin-like growth factor 1 (IGF-1) has been shown to be associated with fertility, growth, and development in cattle. The aim of this study was to (1) identify novel single nucleotide polymorphisms (SNPs) in the bovine ...