Browsing Technological University of the Shannon: Midlands Midwest by Author "Afiadenyo, Michael"
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In silico identification of potential PvFKBP35 inhibitors from Entadrophragma angolense Limonoids extracts as antimalarial agents
Adams, Latif; Issahaku, Abdul; Agoni, Clement; Afiadenyo, Michael; Kusi, Kwadwo Asamoah; Moane, Siobhan; Obiri-Yeboah, Dorcas; McKeon-Bennett, Michelle (Elsevier, 2023-08-05)Plasmodium species, which are spread by female Anopheles mosquitoes, are responsible for malaria. Out of the five major Plasmodium species, Plasmodium falciparum and Plasmodium vivax are the most deadly and invasive species ... -
In silico screening of phytochemicals from Dissotis rotundifolia against Plasmodium falciparum Dihydrofolate Reductase.
Adams, Latif; Afiadenyo, Michael; Kwofie, Samuel; Wilson, Michael D.; Kusi, Kwadow Asamoah; Obiri-Yeboah, Dorcas; Moane, Siobhan; McKeon-Bennett, Michelle (Elsevier, 2023-04-01)Background: Malaria remains a major health concern in developing countries with high morbidity and mortality, especially in pregnant women and infants. A major obstacle to the treatment of malaria is a low effectiveness ... -
An in vitro and in silico investigation of the antitrypanosomal activities of the stem bark extracts of Anopyxis klaineana (Pierre) Engl
Adams, Latif; Obiri-Yeboah, Dorcas; Afiadenyo, Michael; Hamidu, Sherif; Aning, Abigail; Ehun, Ebenezer; Shiels, Katie; Joshi, Akanksha; Sakyimah, Maxwell Mamfe; Kusi, Kwadwo Asamoah; Ayi, Irene; McKeon-Bennett, Michelle; Moane, Siobhan (Cell Press, 2024-03-16)African Trypanosomiasis caused by trypanosome parasites continues to be a major neglected health problem, particularly in developing countries. Current treatments are marked by serious side effects, low effectiveness, ...