Browsing Technological University of the Shannon: Midlands Midwest by Author "Abidin, Ismin Zainol"

Now showing items 1-3 of 3

    • A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix 

      Abidin, Ismin Zainol; Rezoagli, Emanuele; Simonassi-Paiva, Bianca; Fehrenbach, Gustavo Waltzer; Masterson, Kevin; Pogue, Robert; Cao, Zhi; Rowan, Neil; Murphy, Emma J.; Major, Ian (MDPI, 2020-12-06)
      This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to reduce relapse by eradicating ...

    • Chitosan-(poly)acrylic acid polyelectrolyte complexes: enhanced mucoadhesion and sustained drug release in vaginal tablets 

      Abidin, Ismin Zainol; Fehrenbach, Gustavo Waltzer; Gately, Noel (Elsevier, 2024-03-08)
      Polyelectrolyte complexes (PECs) have emerged as promising vehicles for medical applications, attributable to their non-toxicity, non-immunogenicity, and ability for controlled drug release. Notably, their inherent ...

    • A systematic review of mucoadhesive vaginal tablet testing 

      Abidin, Ismin Zainol; Murphy, Emma J.; Fehrenvbach, Gustavo Waltzer; Rezoagli, Emanuele; Gately, Noel; Major, Ian (AboutScience, 2023-01-16)
      Drug administration through the vaginal tract is one of the oldest modalities of pharmacotherapy, and it is also one of the most explored. Since the vaginal cavity has a wide surface area, a plentiful blood supply, and a ...