Browsing Technological University of the Shannon: Midlands Midwest by Title
Now showing items 267-286 of 1332
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Development of a low-temperature extrusion process for production of GRAS bioactive-polymer loaded compounds for targeting antimicrobial-resistant (AMR) bacteria
(Elsevier, 2021-08-10)Antimicrobial resistance (AMR) is recognised globally as one of the greatest threats to human and animal health; thus, discovery of alternative antibacterial agents to address AMR is a priority challenge. This study ... -
The development of a melt-extruded shellac carrier for the targeted delivery of probiotics to the colon.
(MDPI, 2017-12)Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery resulting in improved ... -
Development of a multi-layered vaginal tablet containing Dapivirine, Levonorgestrel and Acyclovir for use as a multipurpose prevention technology.
(Elsevier, 2016-07)Multipurpose prevention technologies (MPTs) are preferably single dosage forms designed to simultaneously address multiple sexual and reproductive health needs, such as unintended pregnancy, HIV infection and other ... -
Development of a new bone scaffold for the treatment of large bone defects
(Athlone Institute of Technology, 2020-06)Large bone defects are typically caused by incidents such as fractures, diseases, trauma or surgeries. Worldwide more that 3/5 million bone grafts (either autografts or allografts) are performed each year. -
Development of a new bone scaffold for the treatment of large bone defects
(Technological University of the Shannon Midlands Midwest, 2022)Large bone defects remains a major problem in orthopaedic surgery despite these advances in medical techniques. To date, autogenous bone grafting is still commonly therapeutic standard. However, it presents some ... -
Development of a reusable learning object for use in teaching structural engineering.
(AIT, 2013)Reusable learning objects may be considered to be pre-developed digital learning activities that may be integrated into lessons, modules, and courses. Their advantages include their flexibility of content, their accessibility ... -
Development of a versatile monitoring technique for real-time protein activity tracking within cellular environment and biomimetic tissue engineering scaffold systems
(Athlone Institute of Technology, 2020-06)Crowded cellular environments with complex and intricate molecular interactions underpin biological processes. High biological noise is intrinsic within these biological systems, and this poses critical challenges to ... -
The development of advanced smart polymer formulations for potential biomedical applications.
(Athlone Institute of Technology, 2020-10)In the past twenty years, a theme in the pharmaceutical industry is to move towards more efficient use of active pharmaceutical ingredients and the need for improved delivery systems. Smart polymers throughout the literature ... -
Development of alginate beads with encapsulated jabuticaba peel and propolis extracts to achieve a new natural colorant antioxidant additive.
(Elsevier, 2020-07)This work aims to encapsulate anthocyanins and phenolic compounds extracted from a native Brazilian fruit peel - jabuticaba (Plinia cauliflora (Mart.) Kausel) and propolis from Tubuna (Scaptotrigona bipunctata) stingless ... -
Development of Amoxicillin loaded microspheres for anti-Helicobacter pylori infection using Ionic Gelation method
(IJASRM, 2017-11)The aim of this project was to develop microspheres loaded with Amoxicillin for anti-Helicobacter pylori infection. Amoxicillin loaded microspheres were developed using blends of natural polymers such as Alginate and ... -
Development of biphasic drug delivery PVA/propolis electrospun nanofibres
(Athlone Institute of Technology, 2020-06)The integration of nanotechnology into biomedical applications is called “nanomedicine”. Nanomedicine has the ability to change properties of materials at the molecular and atomic level [1]. Numerous methods have been ... -
Development of dental implants with antimicrobial activity
(Technological University of the Shannon Midlands Midwest, 2022)Planktonic bacteria are capable of forming biofilms, which are described as microbial aggregates embedded within a matrix of extracellular polymeric substances (EPS) and are found attached to abiotic or biotic surfaces ... -
Development of disulfiram-loaded vaginal rings for the localised treatment of cervical cancer.
(Elsevier, 2014-11)Cervical cancer is the third most prevalent cancer in women and disproportionately affects those in low resource settings due to limited programs for screening and prevention. In the developed world treatment for the disease ... -
Development of drug eluting biodegradable nanocomposite for use in coronary stents
(Athlone Institute of Technology, 2021-07)Coronary stents are the scaffolds placed inside the blocked arteries, which aids the restoration of the passage of blood to the heart. Coronary stenting has become a standard medical procedure to treat coronary heart disease ... -
Development of electrospun PVA nanofibers via freeze-thawing method
(Athlone Institute of Technology, 2019)The polyvinyl alcohol (PVA) hydrogels are proven to have the benefits of improving water retention ability, cell attachment and controlled drug release in medical device materials for pharmaceutical applications. Due to ... -
Development of high strength nanocomposite for biodegradable stents
(Athlone Institute of Technology, 2018-04-24)The use of biodegradable polymer materials are considered to be good alternatives in urology (Donohue et. al. 2018), cardiovascular (Brie et. al. 2016) and tracheal airway stenosis which provide support before it is absorbed ... -
Development of multifunctional hydrogels for the delivery of drugs and nutrients for patients with inflammatory bowel disease
(Athlone Institute of Technology, 2020-06)Inflammatory Bowel Disease (IBD) is a group of diseases that affect the gastrointestinal tract (GI). Comprised of Crohn’s Disease (CD) and Ulcerative Colitis (UC), it affects 6.8 million people globally. IBD is characterised ... -
A development of new material for 4D printing and the material properties comparison between the conventional and stereolithography polymerised NVCL hydrogels
(MDPI, 2022-11-22)The term 4D printing refers to the idea that the shape or properties of a printed object can be changed when an external stimulus is applied. In this contribution, a temperature-responsive polymer Poly (N-vinyl caprolactam) ... -
The development of novel bioresorbable medical devices for treating diseases of the anal canal
(Athlone Institute of Technology, 2020-06)Anal abscesses and fistulae in ano are the most prominent diseases of the anal canal Abscesses are pockets of pus caused by accumulating bactera whereas fistulae in ano are hollow tunnels that protrude from the wall of ... -
Development of novel hydrogel based composites for bone tissue engineering applications.
(2013)The process of tissue engineering involves replacing and assisting in the healing of damaged tissues. Specifically for bone tissue repair, a clinical demand has developed for alternative materials to replace the existing ...