Now showing items 1-4 of 4
An alternative to Triton X-100 for use in viral inactivation for recombinant factor VIII /
Solvent detergent combinations for viral inactivation have long been used in the manufacture of Biopharmaceutical products due their proven safety record for inactivating viruses. Triton X-100, a non-ionic detergent, has ...
Plethora of Potential Platforms: a review of current and future trends in expression system choice in the biopharmaceutical industry /
In the thirty years since the first biopharmaceuticals were approved for use in humans, the choice of expression system for new biopharmaceuticals has remained largely unchanged and is still mainly determined by the necessity ...
A review of chromatography methods for the large scale downstream protein purification of monoclonal antibodies /
Researchers have continually proposed new non-chromatographic methods for manufacturing biopharmaceutical products. However, this report will show that chromatography remains the backbone of the downstream operation. ...