Browsing Conference Paper - School of Science, ATU Galway City by Author "Hogan, Edward L."
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Implications of lymphocyte anergy to glycolipids in multiple sclerosis (MS): iNKT cells may mediate the MS infectious trigger
Hogan, Edward L.; Podbielska, Maria; O’Keeffe, Joan (2013)Immunogenic lipids may play key roles in host defenses against infection and in generating autoimmune inflammation and organ-specific damage. In multiple sclerosis (MS) there are unequivocal autoimmune features and ... -
iNKT-cells and their ligands: focus on multiple sclerosis
O’Keeffe, Joan; Podbielska, Maria; Hogan, Edward L. (2015)The cells of the immune system are broadly divided into those that belong to the innate arm of immunity and those that belong to the adaptive immune system(1) The innate immune cells include macrophages, dendritic cells ... -
Invariant natural killer T-cell anergy to endogenous myelin acetyl-glycolipids in multiple sclerosis
Gately, Carol M.; Podbielska, Maria; Counihan, Timothy; Hennessy, Michael; Leahy, Teresa; Moran, Anthony P.; Hogan, Edward L.; O'Keeffe, Joan (Elsevier, 2013)Objective: To extend our studies on the glycolipid-reactive invariant Natural Killer T-cell (iNKT-cell) function in multiple sclerosis (MS), we investigated the stimulatory activities of two myelin-derived glycolipids which ...