Bioscience Research Institute (Midlands)
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Copyright: All material deposited in the repository must be compliant with Irish copyright legislation. Please refer to: http://www.irishstatutebook.ie/2000/en/act/pub/0028/index.html For items where publisher agreements exist, publishers’ policies must be honoured. A list of publishers’ copyright and self-archiving policies can be found on the Sherpa-Romeo site http://www.sherpa.ac.uk/romeo/ . The author must contact the publisher directly if the publisher is not listed on that site or if written permission to deposit material in a repository is sought. The author must be clear on whether the publisher allows a pre-print, post -print or publisher final version to be added to the repository. Sherpa- Romeo defines pre-prints as being the version of the paper before peer review and post-prints as being the version of the paper after peer-review, with revisions having been made. http://www.irishstatutebook.ie
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In silico identification of potential PvFKBP35 inhibitors from Entadrophragma angolense Limonoids extracts as antimalarial agents
(Elsevier, 2023-08-05)Plasmodium species, which are spread by female Anopheles mosquitoes, are responsible for malaria. Out of the five major Plasmodium species, Plasmodium falciparum and Plasmodium vivax are the most deadly and invasive species ... -
Studies on the novel effects of feeding non-thermally treated honeybee gathered pollen on the colony stability and outputs of commercially-reared bumble bees ( Bombus terrestris) for pollination services
(Technological University of the Shannon: Midlands Midwest, 2023-05)Pollination is a vital resource, carried out mainly by animals, which without could threaten food security on a global scale. Of the agricultural crops that are produced globally, animal pollination is responsible for ... -
Bioprocessing and the production of antiviral biologics in the prevention and treatment of viral infectious disease
(MDPI, 2023-05-17)Emerging, re-emerging and zoonotic viral pathogens represent a serious threat to human health, resulting in morbidity, mortality and potentially economic instability at a global scale. Cer tainly, the recent emergence ... -
Modification of hyaluronic acid to enable click chemistry photo-crosslinking of hydrogels with tailorable degradation profiles
(Elsevier, 2023-06-15)Hyaluronic acid (HA) is a naturally occurring mucopolysaccharide that, due to its inherent bioactivity and extracellular matrix-like structure, has the potential to be utilised extensively in tissue engineering. However, ... -
Role of ascomycete and basidiomycete fungi in meeting established and emerging sustainability opportunities: a review
(Taylor & Francis, 2023-04-27)Fungal biomass is the future’s feedstock. Non-septate Ascomycetes and septate Basidiomycetes, famously known as mushrooms, are sources of fungal biomass. Fungal biomass, which on averagely comprises about 34% protein ... -
Performance of Biomass and Exopolysaccharide Production from the Medicinal Mushroom Ganoderma lucidum in a New Fabricated Air-L-Shaped Bioreactor (ALSB)
(MDPI, 2023-02-22)Conventional stirred-tank bioreactor (STR) designs are optimised for cultures of bacteria but not fungal cultures; therefore, a new Air-L-Shaped Bioreactor (ALSB) was fabricated. The ALSB was designed to eliminate the wall ... -
Editorial: "The value of microbial bioreactors to meet challenges in the circular bioeconomy".
(Frontiers, 2023-04-05)The use of microbial bioreactors has harnessed immense attention to support many of the United Nation’s Sustainable Development Goals where this innovative platform provides crucial insights into unlocking a diversity ... -
A review of Spaulding's classification system for effective cleaning, disinfection and sterilization of reusable medical devices: viewed through a modern-day lens that will inform and enable future sustainability
(Elsevier, 2023-03-22)Despite advances in medicine and innovations in many underpinning fields including disease prevention and control, the Spaulding classification system, originally proposed in 1957, remains widely used for defining the ... -
Studies on the comparative effectiveness of x-rays, gamma rays and electron beams to inactivate microorganisms at different dose rates in industrial sterilization of medical devices
(Elsevier, 2023-03-17)The radiation resistance of Bacillus pumilus spores to gamma rays, X-rays, and electron beam (e-beam) was investigated using industrial irradiators operating at various dose rates. The dose rates were as follows: gamma ... -
Packaging environmental impact on seafood supply chains: a review of life cycle assessment studies
(Wiley, 2022)Packaging is fundamental for food preservation and transportation but generates an environmental burden from its production and end-of-life management. This review evaluates packaging contribution to the environmental ... -
Implications for the seafood industry, consumers and the environment arising from contamination of shellfish with pharmaceuticals, plastics and potentially toxic elements: a case study from Irish waters with a global orientation
(Elsevier, 2022-10-20)Shellfish are a rich source of minerals, B-vitamins and omega-3 to the human diet. The global population is expected to reach 9.6 billion people by 2050 where there will be increased demand for shellfish and for sustained ... -
A circular economy framework for seafood waste valorisation to meet challenges and opportunities for intensive production and sustainability
(Elsevier, 2023)There is a growing concern among societies and consumers over food security and the sustainability of food production systems. For seafood, it has been highly advocated as a healthy food source and its sustainability ... -
Pathogenic drug resistant fungi: a review of mitigation strategies
(MDPI, 2023-01-13)Fungal pathogens cause significant human morbidity and mortality globally, where there is a propensity to infect vulnerable people such as the immunocompromised ones. There is increasing evidence of resistance to antifungal ... -
Hallmarks of aging and immunosenescence: connecting the dots
(Elsevier, 2022-06)Aging is a natural physiological process that features various and variable challenges, associated with loss of homeostasis within the organism, often leading to negative consequences for health. Cellular senescence occurs ... -
The design, development, and testing of novel next generation in vitro agar-based urethral models for medical device innovation
(Technological University of the Shannon: Midlands Midwest, 2022-04)Catheters are one of the most utilised medical devices in modern medicine with catheter associated urinary tract infections (CAUTI) being ubiquitous in worldwide healthcare settings. These infections negatively affect ... -
A risk assessment-based control strategy to formulate a potent, efficacious, and non-invasive topical onychomycotic dosage form
(Technological University of the Shannon: Midlands Midwest, 2021)This project involves the development of a strategy to formulate a novel dosage form with modified coconut oil (MCO) as the active pharmaceutical ingredient to treat onychomycosis caused by T. rubrum and C. albicans. ... -
Critical studies on the novel development and implementation of Vaporized Hydrogen Peroxide (VH2O2) for terminal sterilization of medical devices encompassing use of flow cytometry for the real-time commensurate monitoring of microbial inactivation
(Technological University of the Shannon: Midlands Midwest, 2022-09)Aims and Rationale: Sterilization microbiology relies on determining the linearity of microbial survivor curves for calculating decimal reduction times (D-values) that is used to inform sterility assurance levels (SAL), ... -
A study of network intrusion detection systems using artificial intelligence/machine learning
(MDPI, 2022-11-18)The rapid growth of the Internet and communications has resulted in a huge increase in transmitted data. These data are coveted by attackers and they continuously create novel attacks to steal or corrupt these data. The ... -
Roles of medicinal mushrooms as natural food dyes and dye-sensitised solar cells (DSSC): synergy of zero hunger and affordable energy for sustainable development
(MDPI, 2022)In 2015, approximately 195 countries agreed with the United Nations that by 2030, they would work to make the world a better place. There would be synergies in accomplishing the 17 Sustainable Development Goals (SDGs). ... -
Geobacillus stearothermophilus and Bacillus atrophaeus spores exhibit linear inactivation kinetic performance when treated with an industrial scale vaporized hydrogen peroxide (VH2O2) sterilization process
(Wiley, 2022)Many medical devices are supplied as sterile for safe patient care (McEvoy and Rowan 2019). The global sterilization services market is projected to reach USD 5.5 billion by 2026, growing at a compound annual growth rate ...